SEROQUEL

Medications

Should You Ask

Medication is an essential part of treatment for many people with bipolar disorder. There are different types of medications used to treat bipolar disorder, such as those for depressive episodes and those for manic episodes. Some people with bipolar disorder are treated with combinations of medications. Because bipolar disorder is a lifelong condition, changes in medications or doses may be necessary during different stages of the illness.

Getting used to any new medication takes time. This can be frustrating and difficult to deal with, but it’s important to give your medication time to start working so you can see improvements and work toward getting back to your everyday life. Ask your health care provider questions about your treatment and find out how long it may take for it to work to help set your expectations about when you may see improvements.

Remember to never stop taking your medication or change your dosage without talking with your health care provider first.

Side Effects

Medications for bipolar disorder can cause side effects. However, some side effects may lessen or even go away within a few days or weeks. Be sure to talk with your health care provider about the possible side effects you may experience with your medication.

Don’t be discouraged by side effects—there are ways to reduce or manage many of them. Some side effects may seem embarrassing, but sharing them with your health care provider can help you work together to find solutions. Be sure to discuss any concerns you may have about your treatment plan during your next visit. If you’re not sure where to begin, here are some questions to ask your doctor about medication and side effects.

Sticking with Your Treatment Plan

A treatment plan can have poor results if you don’t follow your health care provider’s directions. Here are some suggestions for sticking with your plan:

  • Always take your medication as prescribed by your health care provider
  • If you have trouble remembering to take your medications, find ways to remind yourself—set an alarm or pager, leave yourself a voicemail message, or ask a friend or family member to help. You can also use the Reminder Calendar to help keep track of your medications
  • If you start to feel better, don’t stop taking your medication. Staying on treatment can help keep your symptoms under control and reduce the likelihood of your symptoms returning
  • Keep your appointments with your health care providers. It’s important to let them know how you are feeling to monitor your progress

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Important Safety Information about SEROQUEL

This is not a complete summary of safety information. Please discuss the full Prescribing Information with your health care provider.

SEROQUEL is approved to treat the depressive episodes and the acute manic episodes in bipolar disorder.

Elderly patients with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) treated with this type of medicine are at an increased risk of death, compared to placebo (sugar pill). SEROQUEL is not approved for treating these patients.

Antidepressants have increased the risk of suicidal thoughts and actions in some children, teenagers, and young adults. Patients of all ages starting treatment should be watched closely for worsening of depression, suicidal thoughts or actions, unusual changes in behavior, agitation, and irritability. Families and caregivers should watch patients daily and report these symptoms immediately to the physician. SEROQUEL is not approved for patients under the age of 18 years.

High blood sugar and diabetes have been reported with SEROQUEL and medicines like it. If you have diabetes or risk factors such as obesity or a family history of diabetes, ask your doctor about checking your blood sugar before starting SEROQUEL and regularly throughout treatment. If you develop symptoms of high blood sugar or diabetes, such as excessive thirst or hunger, increased urination, or weakness, contact your doctor. Complications from diabetes can be serious and even life threatening.

A rare, but potentially fatal, side effect reported with SEROQUEL and medicines like it is neuroleptic malignant syndrome (NMS). Tell your doctor if you have very high fever; rigid muscles; shaking; confusion; sweating; changes in pulse, heart rate, or blood pressure; or muscle pain and weakness because treatment should be stopped if you have NMS.

Another serious side effect reported with SEROQUEL and medicines like it is tardive dyskinesia (TD)—uncontrollable movements of the face, tongue, or other parts of the body. TD may become permanent, and the risk of TD is believed to increase as the length of time on and the amount of these medications increase. While TD can develop in patients taking low doses for short periods, this is much less common. There is no known treatment for TD, but it may go away partially or completely if treatment is stopped.

Before starting treatment, tell your doctor if you have high cholesterol or have a history of, or are at risk for, seizures or a low white blood cell (WBC) count. An eye exam for cataracts is recommended at the beginning of treatment and every 6 months thereafter. Suicidal thoughts or actions may occur in bipolar disorder; tell your doctor if you have thoughts about death or suicide. During treatment, tell your doctor if you feel dizzy or lightheaded upon standing. Since drowsiness has been reported with SEROQUEL, you should not participate in activities such as driving or operating machinery until you know that you can do so safely. Avoid drinking alcohol while taking SEROQUEL because SEROQUEL increases the effects of alcohol. Avoid becoming overheated or dehydrated while taking SEROQUEL.

The most common side effects are dry mouth, drowsiness, sedation, dizziness, high blood sugar, weakness, constipation, abdominal pain, sudden drop in blood pressure upon standing, sore throat, weight gain, abnormal liver tests, upset stomach, and sluggishness.

Please see Prescribing Information, including Boxed Warnings.

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